rHuman VEGF-121 Protein

Vascular Endothelial Growth Factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, VEGF-A may play a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several variants, one being VEGF-121. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95%. Recombinant human VEGF-121 is a non-glycosylated homodimer, containing two 121 amino acid chains , with a total molecular weight of 28.4 kDa. Endothelial Growth Factor-121 Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Endothelial Growth Factor-121 in immunological assays.