www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Mouse IgG F(ab')2

Catalogue number:
Size:
2 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£266.00 Shipping is calculated in checkout
Purity:

Mouse IgG F(ab')2 fragment was prepared from norma

Alternative Names:

Mouse immunoglobulin Fab; F(ab'); F(ab')2; Fragment antigen-binding

Product Description:

Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them) , activation of the compliment cascade, and opsonization for phagocytosis. This product possesses the F (ab') 2 fragment, recognized by the two F (ab) fragments yielded from the digestion of the antibody below the disulfide bond hinge region. Mouse IgG F (ab') 2 fragment has been tested by SDS-Page and can be utilized as a control or standard reagent in Western Blotting and ELISA experiments.

SDS-PAGE of Mouse IgG F(ab')2 Fragment (
SDS-PAGE of Mouse IgG F(ab')2 Fragment (p/n 010-0104). Lane 1: 5 µL Opal Prestained Marker (p/n MB-210-0500). Lane 2: Reduced Mouse IgG Whole Molecule (p/n 010-0102). Lane 3: Reduced Mouse F(c) Fragment (p/n 010-0103). Lane 4: Reduced Mouse F(ab')2 Fragment (p/n 010-0104). Lane 5: Mouse IgM Kappa Myeloma Protein (p/n 010-0107). Load: 1 µg per lane. Predicted/Observed size: IgG at 50 and 25 kDa; F(c) at 25 kDa; F(ab')2 at 25 kDa; IgM K at 70 and 23 kDa. Observed F(c) Fragment migrates slightly higher.