ATP11A Antibody

Catalogue number:

Add to favourites

600-401-Y92

Supplier:

Rockland Immunochemicals

Size:

100 µg

Currency:
GBP
EUR

£673.00

Shipping is calculated in checkout

This product is no longer available to order.

Applications:

ELISA, IF Microscopy, Western Blot

Antibody Host:

Rabbit

Species Reactivity:

Human, Mouse, Rat

Antibody Type:

Polyclonal

Immunogen:

Anti-ATP11A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the N-terminu

Alternative Names:

ATP11A Antibody, ATPIH, ATPIS, ATPIH, KIAA1021, Probable phospholipid-transporting ATPase IH, ATPase IS

Data sheet: View or download

Product Description:

ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.