TYW4 Antibody
ELISA, Immunohistochemistry, IF Microscopy, Western Blot
Rabbit
H. sapiens (Human); Mus musculus (Mouse); Rat
IgG
Polyclonal
Anti-TYW4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the N-terminus
TYW4 Antibody, PPM2, TYW4, KIAA0547, tRNA wybutosine-synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA yW-synthesizing protein 4
TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. Anti-TYW4 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 76 kDa in Western Blots of specific cell lysates and tissues.