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RSRC1 Antibody

Catalogue number:
600-401-EC4
Size:
100 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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Applications:

ELISA, Immunohistochemistry, IF Microscopy, Western Blot

Antibody Host:

Rabbit

Species Reactivity:

H. sapiens (Human); Mus musculus (Mouse); Rat

Antibody Isotype:

IgG

Antibody Type:

Polyclonal

Immunogen:

Anti-RSRC1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide near the C-terminus

Alternative Names:

RSRC1 Antibody, BM-011, SFRS21, SRrp53, SRRP53, BM-011SRrp53

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Product Description:

The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker. Anti-RSRC1 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 39 kDa in Western Blots of specific cell lysates and tissues.

Immunofluorescence Microscopy of RSRC1 a
Immunofluorescence Microscopy of RSRC1 antibody. Tissue: Rat liver tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: RSRC1 antibody at 20 µg/mL for 1 h at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: RSRC1 is nuclear and cytoplasmic. Staining: RSRC1 as red fluorescent signal.
Immunohistochemistry of RSRC1 antibody.
Immunohistochemistry of RSRC1 antibody. Tissue: Rat liver tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: RSRC1 antibody at 5 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: RSRC1 is nuclear and cytoplasmic. Staining: RSRC1 as precipitated brown signal with blue nuclear counterstain.