EDA1 Antibody
ELISA, Immunohistochemistry, IF Microscopy, Western Blot
Rabbit
H. sapiens (Human); Mus musculus (Mouse); Rat
IgG
Polyclonal
Anti-EDA1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 19 amino acid peptide near the internal region of h
Ectodysplasin A, Ectodermal dysplasia protein, ED1, ED1-A1, ED1-A2, EDA1, EDA2, EDA protein, HED, ODT1, STHAGX1, XHED, XLHED
Ectodysplasin A (EDA1) is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation (1) . It is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells and can be expressed as eight alternatively spliced isoforms in hair follicles and in the epidermis of adult skin (2,3) . EDAs are required during development, and loss or mutation of EDA1 results in a group of developmental disorders identified as ectodermal dysplasia type 1 (4,5) . Anti-EDA1 Antibody has been tested for use in ELISA, immunohistochemistry, immunofluorescence, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 41 kDa in Western Blots of specific cell lysates and tissues.
