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GABA(B) Receptor 1 phospho S923 Antibody

Catalogue number:
612-401-D54
Size:
100 µl
Product is available in:
  • UK
  • Ireland
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Applications:

Western Blot

Antibody Host:

Rabbit

Species Reactivity:

Mus musculus (Mouse); Rat

Antibody Isotype:

IgG

Antibody Type:

Polyclonal

Immunogen:

Anti-GABA(B) Receptor 1 pS923 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surr

Alternative Names:

Gamma-aminobutyric acid type B receptor subunit 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1

Product Description:

GABA (B) Receptor 1 pS923 Antibody detects phosphorylated GABA beta Receptor gamma 1. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser 923 is thought to be important in the regulation of GABAB receptor function. GABA (B) Receptor 1 pS923 antibody is ideal for investigators involved in Neuroscience. Anti-GABA (B) Receptor 1 pS923 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA (B) receptor 1 protein phosphorylated at Ser923 in the appropriate cell lysate or extract.

Western Blot of Rabbit anti-GABA(B) Rece
Western Blot of Rabbit anti-GABA(B) Receptor 1 pS923 antibody. Lane 1: rat synaptic membrane. Lane 2: rat synaptic membrane incubated in λ-Ptase (1200 units for 30 min). Load: 10 µg per lane. Primary antibody: GABAB-R antibody at 1:400 for overnight at 4°C. Secondary antibody: IRDye800™ rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: ~102kDa/~102kDa for GABAB R1 protein phosphorylated at Ser923. Other band(s): none.