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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2070014-93-4
Purity:
99.99
Molecular Formula:
C29H37ClN4O3
Molecular Weight:
525.08
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF-CBP1 hydrochloride reduces LPS-induced inflammatory cytokines expression (IL-1β, IL-6 and IFN-β) in primary macrophages. PF-CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders, including epilepsy and parkinson's disease, et al[1].
