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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
956136-95-1
Purity:
99.59
Molecular Formula:
C25H24F3N3O2
Molecular Weight:
455.47
Mass Spectrometry:
Reference Materials
Alternative Names:
LCQ-908
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro[1][2][3][4]. 10mM
