PF-543 (Citrate)
Catalogue number:
HY-15425A-10mg
Supplier:
Size:
10 mg
Product is available in:
£138.00
Special price until 31 Dec 2025
Normal price £153.00
Shipping is calculated in checkout
Normal price £153.00
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1415562-83-2
Purity:
98.35
Molecular Formula:
C33H39NO11S
Molecular Weight:
657.73
Alternative Names:
Sphingosine Kinase 1 Inhibitor II (Citrate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy[1][2][3].
