Mitoxantrone
Catalogue number:
HY-13502-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
65271-80-9
Purity:
99.58
Molecular Formula:
C22H28N4O6
Molecular Weight:
444.48
Mass Spectrometry:
Reference Materials
Alternative Names:
Mitozantrone; NSC 301739
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 µM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity[1][2][3][4]. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 µM and and 0.8 µM for cowpox and monkeypox, respectively[5]. 10mM
