CARM1-IN-1 (hydrochloride)
Catalogue number:
HY-12759A-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2070018-31-2
Purity:
95.13
Molecular Formula:
C26H22Br2ClNO3
Molecular Weight:
591.72
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CARM1-IN-1 (compound 7g) hydrochloride is a highly potent and selective inhibitor of CARM1 (IC50=8.6 µM, CARM1/PABP1), with low inhibitory activity against PRMT1 and SET7 (IC50 >667 µM). CARM1-IN-1 hydrochloride inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 hydrochloride also inhibits the promoter activity of prostate-specific antigen (PSA) without significant cytotoxicity[1].
