AZ1495
Catalogue number:
HY-111101-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2196204-23-4
Purity:
98.07
Molecular Formula:
C21H31N5O2
Molecular Weight:
385.50
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 µM and 0.023 µM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 µM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL)[1].
