Valproic acid
Catalogue number:
HY-10585-1g
Supplier:
Size:
1 g
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
99-66-1
Purity:
99.72
Molecular Formula:
C8H16O2
Molecular Weight:
144.21
Mass Spectrometry:
Reference Materials
Alternative Names:
VPA; 2-Propylpentanoic acid; Dipropylacetic acid
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 (IC50, 400 µM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7].
