Sunitinib
Catalogue number:
HY-10255A-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
557795-19-4
Purity:
99.69
Molecular Formula:
C22H27FN4O2
Molecular Weight:
398.47
Mass Spectrometry:
Reference Materials
Alternative Names:
SU 11248
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. 10mM
