Inavolisib
Catalogue number:
HY-101562-1mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2060571-02-8
Purity:
99.96
Molecular Formula:
C18H19F2N5O4
Molecular Weight:
407.37
Mass Spectrometry:
Reference Materials
Alternative Names:
GDC-0077; RG6114
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor (IC50=0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3Kα. Inavolisib can be used for the study of breast cancer[1].