Y-27632
Catalogue number:
HY-10071-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
146986-50-7
Purity:
99.91
Molecular Formula:
C14H21N3O
Molecular Weight:
247.342
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4][5][6][7].
