Follistatin
Catalogue number:
GFH41-20
Supplier:
Size:
20 µg
Product is available in:
Purity:
>95% determined by reducing and non-reducing SDS-P
Molecular Weight:
31.7
Alternative Names:
FS, activin-binding protein, FSH-suppressing protein, FSP
- Data sheet: View or download
- MSDS: View or download
Product Description:
Follistatin is an autocrine, activin-binding protein that is ubiquitously expressed with highest expression levels being in the ovary and skin. Follistatin negatively regulates the signaling of Transforming Growth Factor ? (TGF-?) family members, such as activin, bone morphogenic proteins (BMP), myostatin, Growth Differentiation Factor 11 (GDF-11), and TGF-?1. Follistatin functions as an antagonist by binding TGF-? family members to block interaction with their signaling receptors. Follistatin also inhibits the secretion of Follicle-Stimulating Hormone (FSH) from the anterior pituitary.