Human MMP-8, Proenzyme

Matrix metalloproteinases (MMP’s) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. This human proenzyme MMP-8 is isolated from neutrophil granulocytes and becomes highly active when incubated with APMA. It can be used in FRET-basedEnzyme activity assay or served as positive control for zymography, Western blot, IP, and ELISA.