Human MMP-3 100 µl

%3Cp%3EMatrix%20metalloproteinases%20%28MMPs%29%20belong%20to%20a%20family%20of%20secreted%20or%20membrane-associated%20zinc%20endopeptidases%20capable%20of%20digesting%20extracellular%20matrix%20components.%20The%20importance%20of%20MMPs%20in%20tumor%20development%20and%20invasion%20as%20well%20as%20other%20diseases%20is%20well%20known.%20MMP-3%20%28stromelysin-1%2C%20transin-1%29%20has%20been%20shown%20to%20involved%20in%20tumor%20metastasis3%20and%20rheumatoid%20arthritis.%20Therefore%20it%20is%20proposed%20as%20a%20therapeutic%20target%20for%20these%20diseases.%20The%20native%20pro-MMP-3%20is%20Mr%2059/57-kDa%20doublet%2C%20which%20can%20be%20autocatalyzed%20to%20an%20active%20form%20of%2045-kDa%2C%20and%20is%20then%20processed%20partially%20to%20a%20second%20active%20form%20of%2028-kDa.%3C/p%3E