The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet β cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells.
Product Type:
Proteins & Peptides
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
1343.6
Reference:
Hu, C. et al. J. Clin. Invest. 117, 3857 (2007); Martin-Orozco, N. et al. J. Immunol. 171, 6954 (2003).
UNSPSC Code:
12352202
Proteins & Peptides from AnaSpec: