This peptide, a nuclear localisation signal (NLS) peptide, is derived from the Large T antigen residues 47 to 56 (PKKKRKVEDP). It can be used to tag DNA. DNA tagged to this peptide efficiently translocates into the cell nucleus.
Proteins & Peptides
Schirmbeck, R. et al. J. Mol. Med. 79, 343 (2001); Vaysse, L. et al. J. Biol. Chem. 279,5555 (2004).