Rec. h a-synuclein (1-140), HF488 200 µg
Catalogue number:
ANA55457
Supplier:
Size:
200 µg _$$_
Product is available in:
£1031.00
Estimated delivery Thu 16 May
Shipping is calculated in checkout
Shipping is calculated in checkout
Molecular Weight:
14.5
Product Description:
Parkinson's disease (PD) is predominantly a movement disorder resulting from degeneration of dopaminergic neurons in the substantia nigra. The cause of the disease is unknown, but substantial evidence suggests that the aggregation of α-synuclein is a critical step in the etiology of PD. α-Synuclein is an abundant brain protein of 140 residues that is present in high concentration at presynaptic terminals and is found in both soluble and membrane-associated fractions of the brain. Several possible functions have been suggested, among which are vesicle release and trafficking. In vitro incubation in the presence of salt (i.e. 0.1M NaCl) with agitation causes α-synuclein to form fibrils.
Storage Temperature:
-78°C