www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Tranilast

Supplier:
Catalogue number:
t6902-10 mg
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£53.00 Estimated delivery Tue 28 Sep
Shipping is calculated in checkout

Mast cell stabilizer; TRPV2 antagonist, PDGFR inhibitor.

Product Type:

Biochemicals

CAS Number:

53902-12-8

Alternative Names:

Rizaben, N-5'

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

327.34

Reference:

Luo J, Li Y, Yang Y, et al. Role and mechanism of tranilast preventing the progression of tubulointerstilial fibrosis in diabetic kidney diseases. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Dec;38(12):1233-42. PMID: 24384948. Zaher SS, Coe D, Chai JG, et al. Suppression of the allogeneic response by the anti-allergy drug N-(3,4-dimethoxycinnamonyl) anthranilic acid results from T-cell cycle arrest. Immunology. 2013 Feb;138(2):157-64. PMID: 23121382. Subramaniam V, Chakrabarti R, Prud'homme GJ, et al. Tranilast inhibits cell proliferation and migration and promotes apoptosis in murine breast cancer. Anticancer Drugs. 2010 Apr;21(4):351-61. PMID: 20145538. Li Y, Liu FY, Peng YM, et al. Mast cell, a promising therapeutic target in tubulointerstitial fibrosis. Med Hypotheses. 2007;69(1):99-103. PMID: 17257770. Watanabe S, Matsuda A, Suzuki Y, et al. Inhibitory mechanism of tranilast in human coronary artery smooth muscle cells proliferation, due to blockade of PDGF-BB-receptors. Br J Pharmacol. 2000 May;130(2):307-14. PMID: 10807667. Koyama S, Takagi H, Otani A, et al. Tranilast inhibits protein kinase C-dependent signalling pathway linked to angiogenic activities and gene expression of retinal microcapillary endothelial cells. Br J Pharmacol. 1999 May;127(2):537-45. PMID: 10385256.

Structure:

C18H17NO5

Formula:

C18H17NO5

UNSPSC Code:

12352200

Details Cat number & supplier Size Price
Topotecan Hydrochloride t5761-50 mg · LKT Labs
t5761-50 mg
LKT Labs
50 mg £163.00
50 mg
view
Vitamin E v3277-25 g · LKT Labs
v3277-25 g
LKT Labs
25 g £48.00
25 g
view
Topotecan Hydrochloride t5761-10 mg · LKT Labs
t5761-10 mg
LKT Labs
10 mg £96.00
10 mg
view
Vitamin E v3277-5 g · LKT Labs
v3277-5 g
LKT Labs
5 g £34.00
5 g
view
Thiamphenicol Palmitate t2934-500 mg · LKT Labs
t2934-500 mg
LKT Labs
500 mg £53.00
500 mg
view
Thiamphenicol Palmitate t2934-1 g · LKT Labs
t2934-1 g
LKT Labs
1 g £80.00
1 g
view
Zolmitriptan z5745-100 mg · LKT Labs
z5745-100 mg
LKT Labs
100 mg £221.00
100 mg
view