GDF-5
>95% determined by reducing and non-reducing SDS-P
13.727.4
Growth Differentiation Factor 5, GDF5, GDF 5, Bone Morphogenic Protein 14, BMP14, BMP-14, BMP 14, CDMP-1, CDMP1, SYNS2, cartilage-derived morphogenetic protein 1, cartilage-derived morphogenetic protein-1, radotermin, LAP4, OS5
- Data sheet: View or download
- MSDS: View or download
Growth Differentiation Factor 5 (GDF-5), also known as BMP-14, is a member of the Bone Morphogenic Protein (BMP) and Transforming Growth Factor ? (TGF-?) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is expressed in the central nervous system and promotes the survival of dopaminergic neurons in animal models of Parkinson's disease. GDF-5 is also important during chondrogenesis and chondrocyte differentiation.