17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid
Catalogue number:
HY-116115-250ug
Supplier:
Size:
250 µg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1233715-33-7
Molecular Formula:
C22H32O3
Molecular Weight:
344.49
Alternative Names:
17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid
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- MSDS: View or download
- Protocol: View or download
Product Description:
17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy[1].