Daraxonrasib
Catalogue number:
HY-148439-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2765081-21-6
Purity:
99.88
Molecular Formula:
C44H58N8O5S
Molecular Weight:
811.05
Alternative Names:
Daraxonrasib
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- MSDS: View or download
- Protocol: View or download
Product Description:
Daraxonrasib (RMC-6236) is an orally active, non-covalent RAS (ON) inhibitor. Daraxonrasib disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, with EC50 values ranging from 28-220 nM for wild-type KRAS, NRAS, HRAS, and multiple oncogenic RAS variants. Daraxonrasib inhibits pERK. Daraxonrasib has anti-tumor activity against KRAS mutant tumors[1][2][3].