DMOG
Catalogue number:
HY-15893-500mg
Supplier:
Size:
500 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
89464-63-1
Purity:
99.77
Molecular Formula:
C6H9NO5
Molecular Weight:
175.14
Mass Spectrometry:
Reference Materials
Alternative Names:
Dimethyloxallyl Glycine
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo[1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5].