LG100268
Catalogue number:
HY-15340-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
153559-76-3
Purity:
99.39
Molecular Formula:
C24H29NO2
Molecular Weight:
363.49
Mass Spectrometry:
Reference Materials
Alternative Names:
LG268
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
LG100268 (LG268) is a potent, selective and orally active retinoid X receptor (RXR) agonist with EC50 values of 4 nM, 3 nM, and 4 nM for RXR-α, RXR-β, and RXR-γ, respectively[1]. LG100268 displays >1000-fold selectivity for RXR over RAR, the Ki values are 3.4 nM, 6.2 nM and 9.2 nM for RXR-α, RXR-β, and RXR-γ, respectively[2]. LG100268 activates RXR homodimers to induce transcriptional activation. LG100268 can be used for the study of lung carcinogenesisy[3].