Nirogacestat
Catalogue number:
HY-15185-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1290543-63-3
Purity:
99.83
Molecular Formula:
C27H41F2N5O
Molecular Weight:
489.64
Mass Spectrometry:
Reference Materials
Alternative Names:
PF-3084014
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1].