Suramin (sodium salt)
Catalogue number:
HY-B0879A-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
129-46-4
Purity:
99.98
Molecular Formula:
C51H34N6Na6O23S6
Molecular Weight:
1429.17
Mass Spectrometry:
Reference Materials
Alternative Names:
Suramin (hexasodium salt)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor[1]. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 µM), and SirT5 (IC50=22 µM)[2]. Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 µM)[3][4]. Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor[5]. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent[6][7][8].