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Clodronate (disodium tetrahydrate)

Catalogue number:
HY-107794-100mg
Supplier:
Size:
100 mg
Product is available in:
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

88416-50-6

Purity:

99.86

Molecular Formula:

CH10Cl2Na2O10P2

Molecular Weight:

360.92

Mass Spectrometry:

Reference Materials

Alternative Names:

Disodium clodronate (tetrahydrate)

Product Description:

Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl- competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain[1][2].