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PFI-2 (hydrochloride)

Catalogue number:
HY-18627A-50mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1627607-87-7

Purity:

99.48

Molecular Formula:

C23H26ClF4N3O3S

Molecular Weight:

535.98

Mass Spectrometry:

Reference Materials

Alternative Names:

(R)-PFI-2 hydrochloride

Product Description:

PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0  nM and (S)-PFI-2 shows inhibiting activity with IC50  value of 1.0  µM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2].