Futibatinib
Catalogue number:
HY-100818-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1448169-71-8
Purity:
99.90
Molecular Formula:
C22H22N6O3
Molecular Weight:
418.45
Mass Spectrometry:
Reference Materials
Alternative Names:
TAS-120
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM)[1][2][3].