This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1429651-50-2
Purity:
99.80
Molecular Formula:
C17H18N2O4
Molecular Weight:
314.34
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6[1].