Olverembatinib
Catalogue number:
HY-15666-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1257628-77-5
Purity:
99.47
Molecular Formula:
C29H27F3N6O
Molecular Weight:
532.56
Mass Spectrometry:
Reference Materials
Alternative Names:
GZD824; HQP1351
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Olverembatinib (GZD824) is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib strongly inhibits native Bcr-Abl and Bcr-AblT315I with IC50s of 0.34 nM and 0.68 nM, respectively. Olverembatinib has antitumor activity[1]. Olverembatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.