GSK-J4 (hydrochloride)
Catalogue number:
HY-15648F-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1797983-09-5
Purity:
99.01
Molecular Formula:
C24H28ClN5O2
Molecular Weight:
453.96
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 µM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-α production in human primary macrophages with an IC50 of 9 µM. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1[1][2][3].