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3MB-PP1

Catalogue number:
HY-102069-25mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

956025-83-5

Purity:

99.66

Molecular Formula:

C17H21N5

Molecular Weight:

295.38

Mass Spectrometry:

Reference Materials

Product Description:

3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 µM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division[1][2][3].