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7α,25-Dihydroxycholesterol

Catalogue number:
HY-113962-25mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

64907-22-8

Purity:

99.88

Molecular Formula:

C27H46O3

Molecular Weight:

418.65

Alternative Names:

7α,25-OHC

Product Description:

7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2].