Valproic acid (sodium)
Catalogue number:
HY-10585A-25g
Supplier:
Size:
25 g
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1069-66-5
Purity:
99.65
Molecular Formula:
C8H15NaO2
Molecular Weight:
166.19
Mass Spectrometry:
Reference Materials
Alternative Names:
Sodium Valproate; VPA (sodium); 2-Propylpentanoic acid (sodium)
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- MSDS: View or download
- Protocol: View or download
Product Description:
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 µM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7].