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3-Hydroxyoctanoic acid

Catalogue number:
HY-113058-25mg
Supplier:
Size:
25 mg
Product is available in:
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

14292-27-4

Purity:

98.0

Molecular Formula:

C8H16O3

Molecular Weight:

160.21

Product Description:

3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.