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PPADS (tetrasodium)

Catalogue number:
HY-101044-10mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

192575-19-2

Purity:

95.0

Molecular Formula:

C14H10N3Na4O12PS2

Molecular Weight:

599.30

Mass Spectrometry:

Reference Materials

Product Description:

PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 µM. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca2+ exchanger in guinea pig airway smooth muscle[1][2].