Desmosterol
Catalogue number:
HY-113224-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
313-04-2
Purity:
99.84
Molecular Formula:
C27H44O
Molecular Weight:
384.64
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].