This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
325970-71-6
Purity:
98.0
Molecular Formula:
C16H14Br2N4O4
Molecular Weight:
486.11
Mass Spectrometry:
Reference Materials
Alternative Names:
DNA Ligase Inhibitor
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC50 are 10 µM). L67 can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS. L67 also activates the Caspase 1-dependent apoptosis pathway in cancer cells, can be used in cancer research[1][2].