Doramapimod
Catalogue number:
HY-10320-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
285983-48-4
Purity:
99.98
Molecular Formula:
C31H37N5O3
Molecular Weight:
527.66
Mass Spectrometry:
Reference Materials
Alternative Names:
BIRB 796
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM[1][2].