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VU 0364439

Catalogue number:
HY-15476-10mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1246086-78-1

Purity:

99.42

Molecular Formula:

C18H13Cl2N3O3S

Molecular Weight:

422.29

Mass Spectrometry:

Reference Materials

Product Description:

VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM. IC50 Value: 19.8 nM(EC50) Target: mGluR in vitro: in vivo: VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63% remaining) than RLM (2% remaining).