Fatostatin (hydrobromide)
Catalogue number:
HY-14452A-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
298197-04-3
Purity:
99.52
Molecular Formula:
C18H19BrN2S
Molecular Weight:
375.33
Mass Spectrometry:
Reference Materials
Alternative Names:
125B11 (hydrobromide)
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- MSDS: View or download
- Protocol: View or download
Product Description:
Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[1][2].