MSA-2
Catalogue number:
HY-136927-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
129425-81-6
Purity:
99.81
Molecular Formula:
C14H14O5S
Molecular Weight:
294.32
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. MSA-2 shows EC50s of 8.3 and 24 µM for human STING isoforms WT and HAQ, respectively. MSA-2 stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models[1][2].