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NSC 617145

Catalogue number:
HY-110185-10mg
Supplier:
Size:
10 mg
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

203115-63-3

Purity:

99.53

Molecular Formula:

C13H10Cl4N2O4

Molecular Weight:

400.04

Mass Spectrometry:

Reference Materials

Product Description:

NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases[1].