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2-MeS-ADP (trisodium)

Catalogue number:
HY-108648-10mg
Supplier:
Size:
10 mg
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

475193-31-8

Purity:

99.90

Molecular Formula:

C11H14N5Na3O10P2S

Molecular Weight:

539.24

Mass Spectrometry:

Reference Materials

Alternative Names:

2-Methylthioadenosine diphosphate (trisodium); 2-Methylthio-ADP (trisodium)

Product Description:

2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1[1][2][3]. 10 mM * 1854 µL in Water